Ionophore-based potentiometric PVC membrane sensors for determination of phenobarbitone in pharmaceutical formulations

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Ionophore-based potentiometric PVC membrane sensors for determination of phenobarbitone in pharmaceutical formulations.

The fabrication and development of two polyvinyl chloride (PVC) membrane sensors for assaying phenobarbitone sodium are described. Sensors 1 and 2 were fabricated utilizing β- or γ-cyclodextrin as ionophore in the presence of tridodecylmethylammonium chloride as a membrane additive, and PVC and dioctyl phthalate as plasticizer. The analytical parameters of both sensors were evaluated according ...

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PVC Membrane Sensors for Potentiometric Determination of Acebutolol

The construction and general performance characteristics of two novelpotentiometric membrane sensors responsive to the acebutolol are described. Thesensors are based on the use of ion-association complexes of acebutolol (AC) withtetraphenylborate(TPB) (I) and phosphomolybdate(PM) (II) as exchange sites in a PVCmatrix. The sensors show a fast, stable and near- Nernstian for the mono charge catio...

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Ionophore-Based Potentiometric Sensors for the Flow-Injection Determination of Promethazine Hydrochloride in Pharmaceutical Formulations and Human Urine

Plasticised poly(vinyl chloride)-based membranes containing the ionophores (α-, β- and γ-cyclodextrins (CD), dibenzo-18-crown-6 (DB18C6) and dibenzo-30-crown-10 (DB30C10) were evaluated for their potentiometric response towards promethazine (PM) in a flow injection analysis (FIA) set-up. Good responses were obtained when β- and γ-CDs, and DB30C10 were used. The performance characteristics were ...

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Potentiometric determination of moxifloxacin in some pharmaceutical formulation using PVC membrane sensors

BACKGROUND The construction and electrochemical response characteristics of Poly (vinyl chloride) membrane sensors for moxifloxacin HCl (MOX) are described. The sensing membranes incorporate ion association complexes of moxifloxacin cation and sodium tetraphenyl borate (NaTPB) (sensor 1), phosphomolybdic acid (PMA) (sensor 2) or phosphotungstic acid (PTA) (sensor 3) as electroactive materials. ...

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Potentiometric determination of dopamine in pharmaceutical preparations by crown ether-PVC membrane sensors.

Two simple, rapid and sensitive sensors for the assay of dopamine hydrochloride have been developed. The methods are based upon the formation of the membrane sensors 12-crown-4-phosphotungestic acid (crown ether-PTA)-dopamine and 12-crown-4-tetraphenylborate (crown ether-TPB)-dopamine as neutral carriers. The sensors were stable and showed fast potential responses of 10 s, and near-Nernstian ca...

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ژورنال

عنوان ژورنال: Acta Pharmaceutica

سال: 2016

ISSN: 1846-9558

DOI: 10.1515/acph-2016-0042